Efficacy and tolerability of benzodiazepines versus antidepressants in anxiety disorders: a systematic review and meta-analysis
Offidani E, Guidi J, Tomba E, Fava GA
Psychother Psychosom. 2013;82(6):355-62.
Benzodiazepines as a Monotherapy in Depressive Disorders: A Systematic Review
Benasi G, Guidi J, Offidani E, Balon R, Rickels K, Fava GA.
Psychother Psychosom. 2018;87(2):65-74.
International Task Force on Benzodiazepines
Balon R, Chouinard G, Cosci F, Dubovsky SL, Fava GA, Freire RC, Greenblatt DJ, Krystal JH, Nardi AE, Rickels K, Roth T, Salzman C, Shader R, Silberman EK, Sonino N, Starcevic V, Weintraub SJ.
Psychother Psychosom. 2018;87(4):193-194.
What psychologists need to know about psychotropic medications
Tomba E, Guidi J, Fava GA.
Clin Psychol Psychother. 2018;25(2):181-187.
Mental Pain as a Transdiagnostic Patient-Reported Outcome Measure
Giovanni A Fava, Elena Tomba, Eva-Lotta Brakemeier, Danilo Carrozzino, Fiammetta Cosci, Ajándék Eöry, Tommaso Leonardi, Isabel Schamong, Jenny Guidi
PMID: 31665739 DOI: 10.1159/000504024
The emerging role of euthymia in psychotherapy research and practice
Jenny Guidi, Giovanni A Fava
PMID: 33130526 DOI: 10.1016/j.cpr.2020.101941
Clinical characterization of allostatic overload
Giovanni A. Fava, Bruce S. McEwen, Jenny Guidi, Sara Gostoli, Emanuela Offidani, Nicoletta Sonino,
Psychoneuroendocrinology. 2019 Oct;108:94-101. doi: 10.1016/j.psyneuen.2019.05.028. Epub 2019 May 31.
Staging of mental disorders: systematic review
Cosci F, Fava GA.
Psychother Psychosom. 2013;82(1):20-34.
Methodological Recommendations for Trials of Psychological Interventions
Guidi J, Brakemeier EL, Bockting CLH, Cosci F, Cuijpers P, Jarrett RB, Linden M, Marks I, Peretti CS, Rafanelli C, Rief W, Schneider S, Schnyder U, Sensky T, Tomba E, Vazquez C, Vieta E, Zipfel S, Wright JH, Fava GA.
Psychother Psychosom. 2018;87(5):276-284
The Sequential Integration of Pharmacotherapy and Psychotherapy in the Treatment of Major Depressive Disorder: A Meta-Analysis of the Sequential Model and a Critical Review of the Literature
Guidi J, Tomba E, Fava GA.
Am J Psychiatry. 2016;173(2):128-37.
The Role of Staging in Planning Psychotherapeutic Interventions in Depression
Guidi J, Tomba E, Cosci F, Park SK, Fava GA.
J Clin Psychiatry. 2017;78(4):456-463.
Conceptual and Clinical Innovations of Well-being Therapy
Jenny Guidi & Giovanni A. Fava
International Journal of Cognitive Therapy volume 14, pages196–208 (2021)
Sequential Combination of Pharmacotherapy and Psychotherapy in Major Depressive Disorder
The sequential model emerged from the awareness that the persistence of residual symptoms and the frequent occurrence of psychiatric comorbidity were both associated with poor long-term outcome of major depressive disorder (MDD).
The study aimed to examine the association of the sequential combination of pharmacotherapy and psychotherapy with reduced risk of relapse and recurrence in MDD. Keyword searches were conducted in PubMed, PsycInfo, Web of Science, and the Cochrane Library from inception of each database through November 2019. Randomized clinical trials examining the effectiveness of the sequential use of psychotherapy following response to acute-phase pharmacotherapy in the treatment of adult remitted patients with MDD were selected independently by 2 reviewers.
Seventeen randomized clinical trials met criteria for inclusion in the meta-analysis, with 1 study yielding 2 comparisons (2283 patients overall, with 1208 patients in a sequential treatment arm and 1075 in a control arm). The pooled risk ratio for relapse/recurrence of MDD was 0.84 (95% CI, 0.74-0.94), suggesting a relative advantage in preventing relapse/recurrence for the sequential combination of treatments compared with control conditions. The results of this systematic review and meta-analysis indicate that the sequential integration of psychotherapy following response to acute-phase pharmacotherapy, alone or combined with antidepressant medication, was associated with reduced risk of relapse and recurrence in MDD. The preventive value of the sequential strategy relies on abatement of residual symptoms and/or increase in psychological well-being. The steps for implementing the sequential approach in remitted patients with recurrent MDD are provided.
Read More »The pursuit of euthymia
Giovanni A Fava, Jenny Guidi
World Psychiatry. 2020 Feb;19(1):40-50.
Sequential Combination of Cognitive-Behavioral Treatment and Well-Being Therapy in Depressed Patients with Acute Coronary Syndromes: A Randomized Controlled Trial (TREATED-ACS Study)
Rafanelli C, Gostoli S, Buzzichelli S, Guidi J, Sirri L, Gallo P, Marzola E, Bergerone S, De Ferrari GM, Roncuzzi R, Di Pasquale G, Abbate-Daga G, Fava GA.
Psychother Psychosom. 2020;89(6):345-356.
Well-Being Therapy for Recurrent Depression and Chronic Pain
Erik Rotterman, Jesse H Wright
PMID: 31537000 DOI: 10.1159/000502848
Well-Being Therapy for Depressive Symptoms in Chronic Migraine: A Case Report
Giovanni Mansueto, Fiammetta Cosci
First Published January 27, 2021
The clinical role of well-being therapy.
Guidi J, Rafanelli C, Fava GA.
Nord J Psychiatry. 2018;72(6):447-453
Benzodiazepines can help depression
A recent paper published in Psychotherapy and Psychosomatics by Dr. Fava points to the important role that benzodiazepines may have in managing anxious and mild depression and present many advantages over antidepressants.
Read More »Antidepressants and Withdrawal
In a widely read article on antidepressant withdrawal, which refers to Dr. Fava’s work, The New York Times invited readers to describe their experiences coming off the drugs. More than 8,800 people responded — teenagers, college students, new mothers, empty-nesters, retirees. Read the article here.
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